World Asthma Day 2024 - Asthma Education Empowers

World Asthma Day - Respiratory Research
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World Asthma Day: Respiratory Research

Despite strides in therapeutic development for asthma management, its morbidity and mortality persistently rise, particularly burdening low- and middle-income countries. To address this pressing need for deeper insight into asthma pathogenesis and therapeutic targets, Respiratory Research presents two focused issues that showcase cutting-edge discoveries in the field.  The findings presented in both collections, “Asthma: Towards a Cure” and “Human Precision Cut Lung Slices: an Ex Vivo Platform for Therapeutic Target Discovery and Drug Testing in Lung Disease” will provide exciting discoveries furthering education and speaking to the theme of this year’s World Asthma Day – Asthma Education Empowers.

The first themed collection, "Asthma: Towards a Cure," compiles manuscripts delving into innovative science aimed at addressing the unmet challenge of managing and ultimately curing asthma. Within this collection, authors unveil novel biomarkers predicting therapeutic responses to both emerging and established treatments. Encompassing fundamental, translational, and clinical studies, these manuscripts not only disseminate new approaches but also strive to influence clinical practice and policy.

The second issue, "Human Precision Cut Lung Slices: an Ex Vivo Platform for Therapeutic Target Discovery and Drug Testing in Lung Disease,” spotlights the utility of an experimental platform mirroring the complexities of the in vivo lung environment. While precision cut lung slices (PCLS) have been utilized in respiratory research since the late 1970s, recent innovations have propelled their acceptance and expanded their applications across various domains. From toxicology and drug discovery to lung cancer biology and respiratory pathogen exposure, PCLS derived from both animal models and human lungs have significantly enhanced our understanding of integrated cellular responses, elucidating fundamental mechanisms in lung biology and providing a platform for therapeutic discovery.

Given the global impact of asthma, Respiratory Research is committed to sharing breakthroughs in asthma research, thereby contributing to the advancement of global health initiatives and providing education to both the scientific community and the general public to empower everyone to combat this disease.

 

Cynthia Koziol-White and Reynold A. Panettieri, Jr.

Rutgers University, New Brunswick, New Jersey USA

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Life Sciences > Health Sciences > Clinical Medicine > Diseases > Respiratory Tract Diseases > Asthma

Related Collections

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Lung Involvement in Systemic Autoimmune Disorders: New Frontiers in Diagnostic and Therapeutic Management

Systemic autoimmune disorders frequently involve the lungs, presenting significant challenges in both diagnosis and management. This special edition of Respiratory Research aims to explore the latest advancements in understanding, diagnosing, and treating pulmonary manifestations of autoimmune diseases, highlighting emerging research that bridges immunology, pulmonology, and rheumatology.

The collection will address the evolving landscape of diagnostic techniques, including imaging, pulmonary function testing, and molecular biomarkers for early detection and disease monitoring. Contributions focusing on novel therapeutic strategies—such as biologics, immunomodulatory agents, and precision medicine approaches—are particularly encouraged. Additionally, we seek insights into the pathophysiological mechanisms underlying lung involvement and interstitial lung diseases in conditions such as systemic sclerosis, rheumatoid arthritis, lupus, and vasculitis, among others.

We welcome original research, systematic reviews, review papers and expert perspectives on topics including:

• Early detection and risk stratification of autoimmune-related lung disease

• Innovations in imaging and functional assessment

• The role of autoantibodies and biomarkers in disease progression and treatment response

• Personalized approaches to immunosuppressive and biologic therapies

• Pulmonary complications of novel rheumatologic treatments

• Multidisciplinary management

• Artificial intelligence in patient-centered care

By bringing together cutting-edge research, this special edition aims to foster a deeper understanding of autoimmune-related lung disease and inform future diagnostic and therapeutic strategies. We invite researchers and clinicians to contribute to this dynamic and rapidly evolving field.

We recognize that many key stakeholders may not have access to such resources and are committed to supporting participation in this issue wherever resources are a barrier. For more information about what support may be available, please visit OA funding and support, or email OAfundingpolicy@springernature.com or contact the Editor-in-Chief.

This Collection supports and amplifies research related to SDG 3, Good Health and Well-Being.

Publishing Model: Open Access

Deadline: Nov 28, 2025

Personalized and Translational medicine

Personalized and translational medicine are emerging medical approaches that have the potential to transform healthcare. It is essential to develop translational biomarkers, diagnostic tests that can predict early therapy response or identify patient subgroups for chronic pulmonary disorders.

This Collection will focus in particular to the areas of chronic lung disease (Asthma, COPD, ILD, IPF, bronchiectasis, others)

- Translational biomarkers

- Preclinical and Clinical imaging studies (MRI, CT, PET/SPECT, optical)

- New translational mouse model

- Diagnostic methods

- Machine learning applications for prognosis and patient stratification

This Collection supports and amplifies research related to SDG 3, Good Health and Well-Being .

We are committed to supporting participation in this issue wherever resources are a barrier. For more information about what support may be available, please visit OA funding and support, or email OAfundingpolicy@springernature.com or contact the Editor-in-Chief.

Publishing Model: Open Access

Deadline: Jul 02, 2026