About Geraldine Zimmer-Bensch
I am a neuroscientist with expertise in neuroepigenetics, particularly in how DNA methylation regulates the development, migration, and functional integration of cortical interneurons. My research combines molecular, cellular, and systems-level approaches—including multi-omics, in vivo models, and behavioral analyses—to understand how epigenetic mechanisms safeguard neuronal subtype identity and mediate environmental influences during brain development. I am especially interested in the role of DNMT1 and long non-coding RNAs in integrating extrinsic cues like ephrins, hormones, and neurotransmitters. My work also explores sex-specific epigenetic regulation and its relevance for neuropsychiatric disorders.
Popular Content
This study reveals how DNMT1 shapes cortical development by guiding interneuron migration and fate specification beyond mitosis, uncovering novel postmitotic functions in neurons and highlighting epigenetic mechanisms relevant to neurodevelopmental disorders.