Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
The long and the short of ACE2, the SARS-CoV-2 receptor
Just six months ago, angiotensin-converting enzyme 2 (ACE2) was hardly in our lexicon, but most people have heard about it by now because SARS-CoV-2 uses it as a receptor to enter cells. We explored the long and the short of ACE2: its transcriptionally independent and functionally distinct isoforms.
Amoeboid aggressive melanoma: non-canonical Wnt signals in cells "leaving at the edge"
Our work published in Nature Communications describes how non canonical Wnt signalling supports melanoma stem cell properties and amoeboid invasion. We observe such tight regulation at the tumour invasive front. This set of signals supports tumour growth and metastasis.
After the Paper: Rising higher than ever – where the electricity eating microbes and hunters are now
Two PhDs and several papers later