Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Protocols & Methods
Bioconjugates of photon-upconversion nanoparticles for cancer biomarker detection and imaging
Photon-upconversion nanoparticles that convert two or more low-energy photons to one photon of UV, visible or NIR light enable the detection and imaging of cancer markers without optical background interference.
Exploring the virtual chemical space with deep learning-accelerated docking
We have developed a deep learning method for large-scale virtual screening in a fraction of the time required by conventional docking. Deep Docking can be used in conjunction with any docking program and enables the screening of billions of compounds in a fast and efficient way.
Cornering the interactome to kill cancer cells
Joshi et al reveal how manipulating cancer cell protein-protein interactions networks (i.e. interactomes) eliminates rebound pathways, turning traditionally less effective therapeutics highly efficacious.