Popular Content
How Post-Translational Modifications Rewire Cellular Networks Through Epichaperomes
Proteins rarely work alone. Their functions emerge from networks of interactions—dynamic connections that continuously reorganize to maintain cellular balance. But what happens when this balance is lost?
Beyond the Headlines: Ensuring Integrity While Advancing Alzheimer’s Research
How do we ensure scientific integrity while advancing urgently needed treatments? Sensationalized media narratives aren’t the answer. While accountability is essential, we must also recognize the groundbreaking research that brings us closer to real solutions for Alzheimer’s and other diseases.
Dysfunctional Protein-Protein Interactome (dfPPI): A Platform for Systems-Level Analysis of PPI Alterations in Disease
Explore Dysfunctional Protein-Protein Interactome (dfPPI): Revealing how aberrant protein interactions drive cancer and neurodegeneration, guiding mechanistic insights and therapeutics innovations.
Unraveling the Sugary Code: N-Glycosylation's Impact on Protein Conformation and its Link to Disease
In the intricate dance of cellular processes, a seemingly modest tweak known as N-glycosylation takes center stage. This post-translational modification endows proteins with a sophisticated sugar code, dictating their conformation, assembly, and, crucially, their roles in various diseases.
Unveiling the Mechanisms Behind Cancer Aggressiveness: How Epichaperomes Drive Cellular Plasticity
What makes cancer so aggressive and adaptable? Our latest research uncovers a hidden mechanism within cells—specialized protein networks called epichaperomes. These structures help cancer cells survive and thrive, reactivating developmental pathways and fueling unchecked growth.
Unveiling Single-Cell Resolution Insights into Epichaperomes in Tissues: Introducing the PU-TCO Clickable Epichaperome Probe
Discovering the secrets of neurodegenerative diseases and cancer at single-cell level precision - the PU-TCO clickable probe illuminates epichaperomes, offering insights into disease mechanisms at a cellular level.