Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
The search for a better protein marker of autophagy
Measuring ATG16L1 phosphorylation as an alternative method to monitor autophagy induction
Beyond the DNA sequence of Clostridioides difficile
Winter 2014, I was revising a grant proposal to develop methods for characterizing bacterial methylomes, the collective DNA methylation events beyond the four canonical bases, G, A, T and C.
Make sustainability science a cumulative effort!
The work life of a researcher working sustainable development can be frustrating at times, owing to widespread pay-wall publishing, poor data reporting practices, and in parts low standards for conducting sound and reproducible research.
Negative selection and neoantigen depletion in the cancer genome: in search for what’s not there
In our latest manuscript we describe a systematic analysis of negative selection pressures acting on neoantigen forming mutations. Contrary to what is generally believed we did not find any clear evidence of this immunogenic form of selection and the resulting neoantigen depletion.
