Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Harnessing Type I CRISPR–Cas systems for genome engineering in human cells
Using a FokI fusion design, we show that Type I CRISPR-Cas systems can be expressed, reconstituted, and faithfully trafficked to the nucleus for genome engineering in human cells
Time-Resolved Serial Femtosecond Crystallography at the European XFEL
The European XFEL (EuXFEL) is an X-ray source that produces femtosecond X-ray pulses at megahertz repetition rates. Time-resolved crystallographic investigations on biological reactions constitute an important class of experiments. We demonstrate how such a reaction is followed at the EuXFEL.
Connecting the dots: adapting innovative antibody technology to improve cancer immunotherapy
Turns out there are times when it’s important to improve on mother nature, especially when confronting a life-threatening disease.
