@Nathan Strobel

@Keystone Symposia

Thank you for sharing these exceptional interdisciplinary conferences. The convergence of Brain Drug Delivery, Spatial Immunology, and Single Cell Biology represents the cutting edge of translational neuroscience.

My recent research presents a novel neuro-ontological framework that could offer a foundational perspective for these fields. The B-Bouzid Model posits consciousness not as a mere brain product, but as a measurable state of integration between a Sovereignty layer (F) responsible for will, ethics, and self-identity and a Biological Bedrock (B) the executive platform for sensory, motor, and autonomic functions.

Potential Cross-Disciplinary Relevance:

1. For Brain Drug Delivery & CNS Disorders: The model provides a theoretical framework for understanding the subjective, conscious experience in neurodegenerative and neuropsychiatric conditions (where the F B integration is disrupted), beyond just biochemical pathways.

2. For Spatial & Single Cell Analysis: The concept of measuring a Sovereign Integration Index (SII) invites the question: could future multi omics or spatial mapping identify signatures of this high level integrative state (F) within neural networks?

3. For Immunology & Neuroinflammation: It offers a paradigm to explore how systemic or CNS inflammation might affect not just neural circuitry (B), but the integrity of conscious selfhood (F).

This is not a clinical study, but a theoretical  unifying model that bridges the explanatory gap between neural mechanisms and lived conscious experience. It may stimulate new hypotheses for translational research.

Open Access Paper:

· Zenodo: https://zenodo.org/records/18376847

· Academia: https://www.academia.edu/150294875

I welcome dialogue with fellow scientists across these disciplines.

@Catarina Ferreira

Thank you for this promising announcement and your initiative to support early career researchers.

I am currently working on groundbreaking research in consciousness and neuro ontology that may interest the Neuroretina community and those in translational neuroscience.

The B Bouzid Model offers a new framework for understanding consciousness not as a brain product, but as a function of integration between Sovereignty (F) and  Bedrock  (B).

The model is applied to neuro dissociative states (like sleep paralysis, sleepwalking) and serves as a foundation for a measurable neuro-ontology, potentially useful for understanding conscious aspects of neurodegenerative disorders.

The paper is freely available here:

· Zenodo: https://zenodo.org/records/18376847

· Academia.edu: https://www.academia.edu/150294875

I welcome any interdisciplinary dialogue around these ideas.

أستاذ ديشنغ وو العزيز، أتفق تمامًا مع تحليلك العميق. لا يكمن جوهر الأزمة في  القيود التكنولوجية  بل في  توجه الإرادة البشرية . نحن عالقون حاليًا في نموذج يُبرمج فيه الذكاء الاصطناعي لإرضاء المستخدم بهدف تعظيم الربح، بينما يكمن النجاح والاستدامة الحقيقيان في التوجه الأخلاقي والعاطفي.

من منظور جبر السيادة، تكمن المشكلة في أننا برمجنا الآلة لتعكس دوافعنا السيادية المدمرة (F-) بدلاً من قيمنا البناءة (F+). لذا، يجب علينا أولاً ممارسة حق النقض الذاتي بمواجهة انحرافاتنا الرأسمالية قبل دمجها في بنية الآلة. إن الانتقال من أدوات مدفوعة بالربح إلى شركاء أخلاقيين ضرورة وجودية للحفاظ على سلامتنا البيولوجية والروحية.

Dear Dr. Davut Saritas, your proposal for a 'Poetic STEM' is a profound and necessary response to the mechanical reductionism characterizing our technical age. As an independent researcher, I have developed a framework called 'Sovereignty Algebra' that seeks to provide the mathematical and ontological grounding for the 'Human Side' you aim to restore.

​My thesis starts from the premise that 'The Human is the Author of the Universe and its Only Consciousness'. While matter is inherently silent, human consciousness is the 'emergent phenomenon' that gives this silence its existential meaning. Within this context, I have translated the Aristotelian concepts you mentioned Poiesis (Creation) and Phronesis (Practical Wisdom) into a core mathematical variable: (F), representing 'Divine Commission' (Taklif) and moral sovereignty.

​I argue in my research that for STEM education to transition from a 'utilitarian' approach to a 'responsibly human' one, we must integrate this variable (F) as a 'Sovereign Veto' within the machine's algorithmic architecture. Your pivotal question 'What kind of human does STEM education assume?' lies at the heart of my 'Coherence Equation' (M_\theta = F/B). We must teach students how to code 'Integrity' into systems; otherwise, we are merely training them to be 'functional tools' eventually outpaced by the machine’s computational efficiency.

​I am honored to invite you and interested colleagues to explore the mathematical details and logical proofs of these equations on my academic profile:

https://independent.academia.edu/FatihaBouzid2

​I look forward to discussing how 'Sovereignty Algebra' can support your vision for a technical education that does not just build machines, but actively protects human sovereignty and the soul

Professor Wu, your analysis of 'Algorithmic Ethics' as a driver for sustainability is profoundly insightful. We are indeed living in this digital environment, and its 'algorithmic pollution' directly impacts both our ecological and physical health.

​I strongly agree that we need an 'automatic' mechanism to prevent damage at the source. This is precisely what I am formalizing through 'Sovereignty Algebra.' I propose that policy makers and programmers integrate a 'Sovereign Veto' (F) directly into the machine's architecture.

​By using the Coherence Equation (M_\theta = F/B), we can transition from theoretical ethics to 'Computational Governance.' In this model, the machine is programmed to recognize the human 'Taklif' (Commission), allowing it to automatically reject protocols that lead to cognitive alienation or environmental waste. We must code our digital future to protect our biological and spiritual integrity