Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Historic floods reveal hidden value of nature for flood defense
We show that flood defenses combining ‘green’ and ‘grey’ features are more beneficial than considered earlier. Beyond wave reduction, ‘green’ salt marshes can lower flood impacts simply by limiting breach size when ‘grey’ engineered structures fail and do so even more effective under sea-level rise
Artificial membraneless compartments in Escherichia coli
Synthetic formation of a type of subcellular membraneless compartment in E. coli upon overexpression of disordered structural proteins such as spider silk and resilin.
NGS-based IGHV SHM analysis in CLL
The most challenging part of NGS-based IGHV analysis in CLL concerns the interpretation of the findings rather than the analysis per se.
ERIC and EuroClonality-NGS are working hard on addressing open issues and on standardization. See Davi et al., Leukemia 2020, doi: 10.1038/s41375-020-0923-9.
A tissue-engineered uterus supports live births in rabbits
This study has been 18 years in the making and is the longest study of my career. It’s a great example of the patience needed to see the science through from beginning to end.