Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Dual-vector rAAVrh8 gene therapy for GM2 Gangliosidosis: a Phase I/II trial
This is a dose escalation of a dual AAV vector gene therapy for Tay-Sachs and Sandhoff diseases in which a novel bithalamic infusion process was used. The broad distribution of axonal connections of thalamic neurons enables transport of the normal B-hexosaminidase A enzyme throughout the cerebrum.
Effectiveness of a Nursing Rehabilitative Intervention for Elderly Victims of Spousal Emotional Abuse on Stress Level, Life Satisfaction, and Family Functioning
Emotional abuse among older couples is a hidden yet harmful issue affecting well-being and family stability. Despite its impact, targeted interventions remain limited. This study evaluates a nursing rehabilitative intervention to improve outcomes among elderly victims.
Political economy of administrative responses to informal housing and land tenure security in Sheger City Ethiopia
The rapid urbanisation of Sheger City, Ethiopia, has led to a proliferation of informal housing and a growing struggle for land tenure security among its residents. This research, published in Discover Cities, delves into the political economy of administrative responses to this phenomenon.