Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Structure-guided engineering of CRISPR-based tools
Wenxia Yu, Yunbo Qiao
Regioirregular Mizoroki-Heck reaction
The "forbidden" alkene regioisomer during The Mizoroki–Heck coupling reaction of acrylates and styrenes, i.e. the alpha coupling product, is now achieved by employing substrate– or zeolite–hindered chemical enviroments with palladium single atom and sub–nanometric cluster catalysts.
Human fetal whole body post-mortem microfocus computed tomographic imaging
Pregnancy loss is a devastating event and whilst conventional autopsy techniques can provide parents with answers as to the cause of their loss, many decline due to its invasive nature. We describe micro-CT as an alternative to conventional autopsy and why this is more acceptable to parents.