Rein in or Ruin: Ubiquitylation of CDC42 Ensures Membrane Homeostasis and Regulates Brain Development
The small Rho GTPase CDC42 drives actin polymerization and membrane protrusion. Unchecked cytoskeletal remodeling can push tumor cells toward EMT or even cell death. Thus, elucidating how cells both activate and quench CDC42 signaling to maintain membrane homeostasis has been a central question.
A comprehensive review of emerging environmental contaminants of global concern
Emerging contaminants like plastics, pharmaceuticals, PFAS, and endocrine disruptors are increasingly found in water, soil, and food. Often unregulated, they threaten ecosystems and health. This review explores their sources, impacts, and detection methods to guide global solutions.
