Imaging glioma metabolism
We sought evidence for the presence of metabolic subtypes in the tumours of glioblastoma patients by infusing the patients with 13C-labelled glucose immediately prior to surgery and then rapidly freezing the excised tumour and subjecting tumour sections to mass spectrometry imaging.
Engineering alcohol dehydrogenase for better utilization of nicotinamide cofactor biomimetics
Jiangnan Univ's Prof. Ye Ni discovered the first natural ADH utilizing synthetic NCBs, advancing synthetic biology & industrial enzyme engineering for enhanced biocatalysis.
Behind the Paper: Potent antagonist for the MAS-related G protein-coupled receptor and its mouse ortholog with anti-inflammatory, anti- asthmatic, and anti-anaphylactic efficacy in human mast cells and mice
This is the story behind the paper by Al Hamwi et al., recently published in Signal. Transduct. Target. Ther. 2025, 10, 128. doi: 10.1038/s41392-025-02209-8.
Nanopore -based ELISA
Providing a new signal output method for enzyme-linked immunosorbent assay (ELISA)
Heterocycle-based dynamic covalent chemistry for dynamic functional materials
Behind story about the heterocycle-based dynamic covalent chemistry and related materials. Artical link: https://www.nature.com/articles/s41467-025-59027-3.
A Chat in the Hallway Leads to Discovery
What can lead to new discovery in science? In this story behind the paper, a chat in the hallway at Argonne sparked a long and fruitful collaboration leading to a significant discovery of effective additives for lithium-ion batteries (LIBs).
Advanced Synthesis of Trimethylene Carbonate: a High-yield Green Route
Prof. Wei Du's team at Tsinghua University developed an enzymatic process for trimethylene carbonate synthesis from 1,3-propanediol and dimethyl carbonate. The green method achieves 88% yield, the highest reported to date, offering industrial potential with mild conditions.