Theraputic Gas Generation and Delivery Platform
The delivery of theraputic gas is an underexplored field, with good drug diffusion and unique subcellular molecular mechanisms. But the limitation is how can we make a wearable gas delivery device that patients can carry it and use it for daily life?
Chemistry-informed recommender system to predict optimal molecular receptors in SERS nanosensors
From Netflix to Nanosensors: A Chemistry-Informed Recommender System for Smarter SERS Sensors. Recommender systems are widely used in our daily lives, can analogous data-driven approaches be applied to suggest optimal recognition elements for nanosensors?
Immobilized acyl-transfer molecular reactors enable the solid phase synthesis of sterically hindered peptides
An immobilized ribosome-mimicking molecular reactor (RMMR) boosts coupling efficiency in the solid-phase synthesis of N-methylated or α,α-disubstituted amino acid(s)-containing sterically hindered peptides, including cyclosporin A and alamethicin F analogues.
Miniature lenses can interpret shape from color in endoscopes
We created a technology that can measure wavefront shape through an incoherent optical fiber, just with one little flat optic at the fiber tip. However to be effective, we needed to create a longitudinal rainbow... a prism that splits colors in the propagation direction of light!
Epigenetics in Motion: How DNMT1 Steers Interneuron Migration and Identity
This study reveals how DNMT1 shapes cortical development by guiding interneuron migration and fate specification beyond mitosis, uncovering novel postmitotic functions in neurons and highlighting epigenetic mechanisms relevant to neurodevelopmental disorders.