Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
It started with a spot: How Staphyloccocus aureus modifies its surface antigens
Staphylococcus aureus is major human pathogen. Its success relies on the multitude and redundancy of immune evasion strategies. In this behind the paper article we describe how a prophage-encoded glycosyltransferase was identified and how it is able to attenuate the immunogenicity of its substrate Wall teichoic acid.
Eventually, we found a substrate!
Identification of a physiological substrate of protease is challenging. We take effort to revealed that a receptor histidine kinase is cleaved by a bacterial protease, which is a prerequisite for the bacterial tolerance to osmolarity stress.
