Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Neuroscience
Four-Scene Circumstances: A Tale of Visual Complexity and Origin
The brain is one of the most intricate structures in life. Its complexity is a result of the vast diversity of neuron types that shapes various aspects of behavior and ultimately determines each species’ survival.
Targeting Stem Cells in Medulloblastoma
Here, we tested the hypothesis that OLIG2, a key transcriptional regulator of neural development, plays a crucial role in maintaining cancer stem cells (CSC) in medulloblastoma tumors that can be exploited using a new type of targeted therapy.
Targeting Cell Fate Transitions in Medulloblastoma: Precision and Context Matter
Research from my lab led by Kinjal Desai, out today in Nature Communications, probes cell fate transitions in the medulloblastoma hierarchy. By blocking OLIG2, which drives the transition from quiescence to proliferation in the neoplastic stem cells, we block de novo tumour formation and regrowth.
Perception and behavior toward neuropsychiatric disorders in Saudi Arabia
This systematic literature review was conducted to examine the most studied neurodevelopmental disorders reported in the Kingdom of Saudi Arabia and explore public knowledge, attitudes, and behaviors.
Synaptogenesis: A Key Process in Alzheimer's Disease (AD)
Understanding how synaptogenesis is affected in AD provides essential insights into disease progression and opens avenues for therapeutic intervention.