Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Neuroscience
Recessive ReNU2 syndrome: highly prevalent and potentially treatable
Genetic variants in a small noncoding gene called RNU2-2 are responsible for the most prevalent known recessive neurodevelopmental disorder. It may also be amongst the disorders amenable to treatment with gene replacement therapy.
Expanding the Spectrum of Autoimmune Encephalitis — A Rare Anti-Recoverin Case
Autoimmune encephalitis (AE) continues to evolve as a diagnostic category, with emerging antibodies expanding both its clinical and mechanistic boundaries. This case report highlights a particularly rare and instructive entity: anti-recoverin antibody–associated autoimmune encephalitis.
Transcranial electrical stimulation for the treatment of obsessive–compulsive disorder
Obsessive–compulsive disorder (OCD) imposes a substantial burden on mental health and is associated with substantial disability. While cognitive behavioral therapy and SSRI medication are considered first-line treatments for OCD, less than 40% of patients respond fully to these treatments.
Human neuronal differentiation under Aβ exposure: a single-cell transcriptomic and epigenomic dataset
What happens when developing human neurons encounter amyloid-β, one of the central molecules linked to Alzheimer’s disease? We followed human neural progenitor cells as they differentiated into neurons to examine how early Aβ exposure reshapes this process.
Is it really true that students from low socioeconomic status (SES) are less creative than high-SES ones?
A new study published in npj Science of Learning shows that conventional creativity assessments (like PISA 2022) conflate students' reading ability. High-SES students outperform low-SES ones only when the assessment embeds reading requirements.