Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Neuroscience
Single cell proteomics of human neutrophils in glioblastoma
Neutrophils infiltrate glioblastomas with the capacity to engage pro/anti tumoural responses. Here we developed single cell proteomic workflows to stratify neutrophil heterogeneity by function. This work provides a platform to study neutrophil proteomes with single cell resolution in glioblastoma.
Behind the paper_ipRGC properties prevent light from shifting the SCN clock during daytime
Our body clock uses light from the eyes to stay in sync with day and night. Light usually resets this clock at night, not during the day. We found that this is partly because light-sensing cells in the eye limit how strongly they signal, helping keep daily rhythms stable.
Thiorphan reprograms neurons to regenerate after spinal cord injury
A Nature study reveals a small drug that helps adult neurons behave more like they did in early development—when growth was possible. In spinal cord injury models, it boosted nerve regeneration and improved hand function, pointing to a new repair strategy.
The First Glimpse of “Resting-State” Activity in the Human Spinal Cord
Even when we’re doing nothing, our brains are far from silent. Networks of brain regions continue to “talk” to each other through subtle, rhythmic fluctuations in activity. The patterns reshape our understanding of how the brain organizes itself.
But what about the spinal cord?
Testing a nature-based family activity intervention for children with attention deficit hyperactivity disorder
“In nature children find space to breathe"
We are exploring whether a nature activity box can be used in NHS Neurodiversity services following a child's ADHD diagnosis. We are working with families and staff members to see how easy it is to use and how it might help quality of life and wellbeing.