World AIDS Day 2019
World AIDS Day started 31 years ago on 1 December 1988
The gut microbiome following acute HIV-1 infection
To our knowledge, this is the most comprehensive prospective study investigating the longitudinal impact of acute HIV-1 infection in an HIV-1 hyperendemic area such as the Manhiça district in Mozambique. This unique study confirms and extends previous findings in non-human primate models and provides critical insights into the impact of infections in the gut microbiome as well as into the pathogenesis of HIV-1 infection.
Immunotherapy against cancer to be used in HIV cure strategy: a proof-of-concept
In the era of suppressive antiretroviral therapy (ART), HIV reservoir cells are the last hurdle in eradicating the virus. Here, we are testing the hypothesis that immunotherapy against cancer potentiates the reactivation of latently infected cells isolated from ART-suppressed individuals favoring their elimination.
Harnessing insights from one child case of post-treatment control of HIV
Individuals who have the ability to control HIV-1 to undetectable levels either naturally in the absence of antiretroviral treatment (ART) (elite controllers), or those who achieve this after starting ART early in infection and later stopping ART (post-treatment controllers) – tell us that HIV remission is possible. This study describes virological and immunological features associated with a single case of durable post-treatment control of HIV-1 in a young South African child.
