Laboratory capacity building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting.

The publication of our article in the Journal of Epidemiology and Global Health presented our team with a unique opportunity to highlight a positive development in a landscape often dominated by negative narratives. In this blog, we will discuss some of the challenges encountered during the project.

Published in Biomedical Research

Laboratory capacity building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting.
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Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting - Journal of Epidemiology and Global Health

Introduction Even before the COVID-19 pandemic, Somalia’s national laboratory services had insufficient diagnostic capacities. We describe how the country moved rapidly from no testing capability to molecular testing and genomic sequencing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogens. Methods We reviewed primary sources information as well as data and records from secondary sources from 1 January 2020 to 31 December 2023. We also analyzed laboratory surveillance data of cases of COVID-19 and other epidemic diseases reported during the same period and the number of laboratory tests performed during the same period. We used this information to demonstrate improvements in laboratory diagnostic capacity in Somalia before, during and after the COVID-19 pandemic. Results The country was able to rapidly scale up testing for SARS-CoV-2 using reverse-transcriptase polymerase chain reaction assays. At the same time, other innovative solutions were used for testing, such as repurposing tuberculosis GeneXpert diagnostic platforms to increase access to testing at points-of-care and introducing antigen rapid diagnostic tests for hard-to-reach communities. Somalia also acquired new generation sequencing capability for detection and characterization of circulating SARS-CoV-2. These laboratory and testing enhancements have enabled Somalia to participate in surveillance for priority diseases and detection of outbreaks caused by emerging pathogens. Conclusion Somalia’s strategic approach to COVID-19 is an inspiring example of resilience and adaptability. Utilizing resources, technology and lessons from COVID-19 enabled the country to increase and improve laboratory services, expand testing capacity, and strengthen workforce capability. As such, Somalia can now better respond to other infectious disease threats and has significantly improved national health security.

The COVID-19 pandemic is remembered as a disease that has shaken the tenets of global health in a significant way. For over three years, from 2020 to 2022, it dominated as the leading cause of cases, hospitalizations, and deaths due to infectious disease, bagging the infamous title of the blockbuster virus of the decade. However, amidst the devastation, the pandemic exposed the underbelly of health security, exposing the gaps in preparedness, response, and recovery.

Additionally, due to limited countermeasures available in the early phase of the disease, testing and tracking infected individuals become the only available weapon to curtail transmission.  This situation placed laboratories, a traditionally neglected sector of the healthcare system, at the center of the response. Indeed, it was time for the laboratory system to emerge from its neglect and assert its essential role in the health security landscape. While countries capitalized on this opportunity to develop their laboratory sectors, it was a particularly valuable opportunity for nations facing resource limitations and ongoing conflicts.

For the Federal Republic of Somalia, the scale-up of the infrastructure and health workforce capacities, along with the provision of state-of-the-art equipment and supplies achieved during this period, was unprecedented compared to any previous intervention from the government, humanitarian/development partners, or the private sector. These efforts were essential to expand access to testing for the population living in diverse settings, some of which were inaccessible due to insecurity. It was deemed important to share this experience through a scientific publication as a successful health program case study and to set a precedent for countries in similar contexts. Therefore, our articles illustrate how the opportunity was effectively utilized to transform the country’s laboratory system showing key milestones in the laboratory sector.

While similar narratives have emerged from other nations, such as Yemen, the context in Somalia differed fundamentally in several respects, some of which are described below:

Starting from scratch

Since the country is emerging from three decades of internal civil conflict, the central government continues to struggle to fulfill its statutory obligations, including providing essential healthcare. As a result, healthcare infrastructure is severely damaged due to years of neglect, the demand for services is overstretched, and the health workforce has limited capacity. Functional laboratories in the country were few and far between, making establishing capacities, especially at the State level, quite challenging owing to the lack of basic amenities like water and electricity.

The nightmare of non-state actors

The laboratory improvement program faced particularly significant challenges because it targeted a third of the population living in the precincts of de facto Non-State actors. Implementing health programs and testing services to hard-to-reach populations sometimes exposed us to risks. Ultimately, achieving the goal outweighed the fear, and the results justified the calculated risks.

Co-occurring health emergencies

The COVID-19 pandemic coincided with persistent outbreaks in the country, such as cholera and measles, which often diverted resources and focus, impeding implementation. Despite this, the global attention on COVID-19 at that time ensured that interventions to address the pandemic remained a top priority.

Of the many achievements reported in the paper related to laboratory and surveillance improvements, two main areas deserve a mention. First, laboratory capacity for molecular, bacteriological, and serological testing has been significantly expanded and improved to enhance surveillance of outbreak-prone diseases in the country. This development strategically positions the country’s public health laboratories on the road to recovery from many years of neglect. It also improves the country’s IHR core capacity and health security index score. Figure 1 below shows the progressive improvement in the number of tests for different endemic diseases.

Figure 1: Showing the number of tests for different endemic diseases performed in public health laboratories between 2020 and 2023.

Second, establishing three genomic sequencing laboratories represents a transformative step toward access to innovative technologies, even in resource-limited settings. For countries reliant on humanitarian agencies for essential health programs, such as immunization programs, this kind of investment would typically be unfeasible during peacetime. However, the urgent necessity for in-country capacity to monitor circulating variants and the limited ability to refer samples outside the nation have underscored the importance of developing substantial local capabilities.

Next steps:

Establishing the infrastructure and installing the equipment are only a few pieces of the puzzle. The major task will be to sustain the progress and ensure the provision of the resources required to maximize the utilization of the established capacity. As interest in COVID-19 waned, complacency has already set in. However, to fill the gaps and ensure the functionality of this investment, leadership and prioritization in resource allocation will be required both at the MOH level and in critical health programs such as WHO.

In conclusion:

The COVID-19 pandemic was a lifetime opportunity for resource-limited, humanitarian-dependent countries to improve their laboratory systems. As reported in our article, this opportunity was well utilized in Somalia. The material infrastructure and human capacity built will be a national asset that will be useful for the generations to come. The lesson learned from COVID-19 should be a wake-up call for countries to prioritize investment in their laboratory systems for the safety and security of their population and as the first line of defense against infectious diseases. In the meantime, laboratory strengthening programs should be viewed as a critical and indispensable part of the healthcare system, even in the context of emergencies and resource limitations. Moreover, resources should be deliberately planned and allocated to ensure continuous improvement while sustaining the gains.

 


 

Parting shot—As leaders assemble for the World Health Assembly in Geneva between May 19th and 27th, 2025, to discuss global health issues, the role of laboratories in ensuring health security should be a standing agenda item followed by actionable resolutions. Indeed, the world should not wait for the next pandemic to realize the critical role laboratory programs play in ensuring health security for all.  


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