Editor
From the Editors

Voltage imaging in the red

New red-shifted genetically encoded voltage sensor for in vivo use
Published in Bioengineering & Biotechnology
Go to the profile of Markus Elsner
Markus Elsner
Senior Editor, Nature Biotechnology
Voltage imaging in the red
Like

Share this post

Choose a social network to share with, or copy the URL to share elsewhere

Share with...

...or copy the link

This is a representation of how your post may appear on social media. The actual post will vary between social networks

Multiplexing optogenetic manipulation and readout requires using the whole optical spectrum. So far, red-shifted genetically encoded voltage indicators have suffered from low sensitivity that limited in vivo use. In a recent paper in Nature Methods, Pieribone and colleagues present VARNAM, a FRET-opsin indicator that is imageable under moderate intensities. The authors show that VARNAM can image action potentials in cell cultures, brain slices and live Drosophila and cortical and hippocampal rhythms in freely behaving mice.

https://www.nature.com/articles/s41592-018-0188-7

Go to the profile of Markus Elsner
Markus Elsner
Senior Editor, Nature Biotechnology

Please sign in or register for FREE

If you are a registered user on Research Communities by Springer Nature, please sign in

Sign In Register

Follow the Topic

Biotechnology
Life Sciences > Biological Sciences > Biotechnology

Recommended Content

Cookies

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website. You can decide for yourself which categories you want to deny or allow. Please note that based on your settings not all functionalities of the site are available.

Further information can be found in our privacy policy.

Cookie Control

Customise your preferences for any tracking technology

The following allows you to customize your consent preferences for any tracking technology used to help us achieve the features and activities described below. To learn more about how these trackers help us and how they work, refer to the cookie policy. You may review and change your preferences at any time.

See the full cookie policy See the full privacy policy
More information

These trackers are used for activities that are strictly necessary to operate or deliver the service you requested from us and, therefore, do not require you to consent.

More information

These trackers help us to deliver personalized marketing content and to operate, serve and track ads.

More information

These trackers help us to deliver personalized marketing content to you based on your behaviour and to operate, serve and track social advertising.

More information

These trackers help us to measure traffic and analyze your behaviour with the goal of improving our service.

More information

These trackers help us to provide a personalized user experience by improving the quality of your preference management options, and by enabling the interaction with external networks and platforms.