Go to the profile of Alex de Mendoza

Alex de Mendoza

  • United Kingdom

About Alex de Mendoza

Interested in the evolution of gene regulatory mechanisms in animals and unicellular eukaryotes.

Intro Content

A brain “zoo” reveals how a non-canonical form of DNA methylation emerged
Nature Ecology & Evolution
Behind the Paper

A brain “zoo” reveals how a non-canonical form of DNA methylation emerged

Most animals use DNA methylation at CG dinucleotides to regulate gene expression. However, we found that a non-CG form of DNA methylation was a much later addition to the epigenetic code that regulates brain transcriptional programs in vertebrates.

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