Go to the profile of Lewis Zhichang Shi

Lewis Zhichang Shi

Professor, The University of Alabama at Birmingham
  • United States of America

About Lewis Zhichang Shi

Immuno-metabolism, Cancer Immunotherapy, T cell biology

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Comment on Gfi1, a newcomer to the realm of T cell exhaustion
Go to the profile of Lewis Zhichang Shi
Lewis Zhichang Shi
Jul 07, 2025

Dear Colleagues,

I'd like to share our recent publication on Gfi1 as a key regulator of T cell exhaustion. Please help take a read. Thanks.

Lewis

Comment on HIF1a-regulated glycolysis promotes activation-induced cell death and IFN-g induction in hypoxic T cells
Go to the profile of Lewis Zhichang Shi
Lewis Zhichang Shi
Nov 13, 2024

I woud lik to share our most recently published story with the research community, wherein we report an indispensable role of HIF1a in driving IFN-g induction in hypoxic T cells and anti-tumor immunity elicited by immune checkpoint blockade therapies. 

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