About Melody Smith
I am a phyisican-scientist at Stanford University. I care for patients with blood cancers who receive bone marrow transplant and adoptive cellular therapies while also leading research in my independent lab. My research investigates the biology of chimeric antigen receptor (CAR) T cells to improve the efficacy and safety of this therapy (1) by investigating donor and third-party CAR T cells in preclinical models of allogeneic hematopoietic cell transplant and (2) by assessing the impact of the intestinal microbiome on CAR T cell response.
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The intestinal microbiome is associated with clinical outcomes after anti-CD19 CAR T cell therapy in patients with B-cell malignancies.