Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
From Citation to Courtroom: When Research Evidence Shapes Legal Reasoning
A CRISPR funding study cited in a U.S. legal brief reveals how scientific evidence informs judicial reasoning. Beyond academia, research quietly shapes legal arguments about public funding, innovation, and societal impact.
Direct antiviral therapy in patients with HCV: evidence from Saudi Arabia
HCV remains a major global health problem, with a lack of empirical data on HCV in Saudi Arabia. This study investigated the current understanding of the clinical impact of direct-acting antiviral (DAA) on HCV infection in Saudi patients.
When pyrite is more than a reducing agent: how arsenic ‘charges up’ uranium mineralisation
By Hao Song (Chengdu University of Technology)
Statistical Errors in Primary Studies: A Way to Improve Meta-Analytic Evidence?
Meta-analyses are only as reliable as the studies they include. This post explores whether tools like statcheck and GRIM can flag statistical errors. While removing flawed studies can shift results, we also encountered practical limits to applying such error-checks at scale.
2-DG reprograms mitochondrial metabolism to rescue CD8 T cells impaired by HIV-1
Antiretroviral therapy (ART) effectively suppresses HIV replication but fails to eradicate HIV reservoirs or fully restore immune function in HIV-infected people. In this study, we sought to define how persistent IFN signaling impairs, and how to rescue, CD8⁺ T cells during HIV infection.
Surveying the chemistry of pest-controlling fungi.
Fungi can be efficient as control agents against plant-pathogenic fungi and insects. But we know little about how they function. As a result, their use presents several challenges, ranging from inconsistent efficacy to concerns about potential negative effects on crops.