Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Ecology & Evolution
Statistical mechanics of pan-genomes: A peek into the Grand Tinkerer’s workshop
To advance our understanding of how evolution shapes prokaryote pan-genomes we need new concepts and models. Using metabolic reactions, we introduced a sampling approach that disentangles the drivers of pan-genome evolution and provides a mechanistic interpretation for gene frequencies.
Sticklebacks and Hopeless Monsters
What types of genes and mutations underlie the striking anatomical differences found in wild species? New genetic research shows that wild stickleback fish evolve major changes in their defensive armor using the vertebrate homologs of the famous Hox genes of Drosophila. Four-winged fruit flies have been described as "hopeless monsters" that would never survive outside the laboratory. However, sticklebacks with different bony spine patterns are thriving under a full range of fitness constraints in natural environments, providing a striking example of how wild vertebrate species evolve new body structures through repeated regulatory mutations in key developmental control genes.
