Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: General & Internal Medicine
Why Recovery, Not Stress, May Be the Missing Biology of Resilience
Stress is inevitable, but recovery is conditional. This Behind the Paper piece explains how bioenergetic limits, mitochondrial throughput, and unresolved recovery may shape resilience, aging, and chronic disease.
A Decade-Long Journey to Ask Whether “Less Can Be More” in Metastatic Colorectal Cancer Treatment
More than ten years ago, we began the C-cubed trial with an important question: can some patients with metastatic colorectal cancer live just as long while starting with a gentler treatment? Our study explored whether delaying oxaliplatin could preserve quality of life without compromising survival.
When Fast Food Becomes Identity: Exploring the Eating Behaviors of Egyptian Female University Students
Why do female university students continue eating fast food despite knowing its risks? Our study explored how identity, social influence, emotions, and university life shape fast-food consumption among Egyptian female students.
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior
Published in Neuropsychopharmacology volume 50, pages1683–1694 (2025)
Key Role of the CRE Sequence in the Per1 Promoter in Mediating the Switch Between Unipolar and Bipolar Depression‐Like Behaviors
Published in Journal of Pineal Research, 2025, https://doi.org/10.1111/jpi.70095
Atrial fibrillation research in rodents, time for better standards?
📢Publication alert: new paper from our lab in Europace📢
Making the Most of Brain Dock: Translating a Uniquely Japanese Screening Tradition into Evidence for Primary Stroke Prevention
Brain Dock is Japan's preventive MRI programme for identifying asymptomatic cerebrovascular abnormalities in apparently healthy individuals. Asymptomatic brain lesions are established stroke risk markers, but evidence that lesion-guided intervention reduces future events remains limited.
Quieting the Inflammatory Storm After Stroke: Insights from the NUVISTA Trial
An interview with Dr. Eric Leuthardt on transcutaneous auricular vagus nerve stimulation in large vessel occlusion stroke
Translational Stroke Exchange Editorial Team