Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
When cancer cells get squeezed: discovering how physical forces shape metastasis
Cancer’s deadliest trait is its spread. Millions of tumor cells enter the bloodstream daily, yet only a few survive and seed metastases. Why these rare cells succeed, while most perish, remains one of cancer research’s greatest mysteries.
Optically Programmable Array of Transducers
Phased Array Transducers (PATs) are used to shape ultrasound. They require complex electronics and are hard to scale, which limits their ability to form sophisticated patterns. Here, we introduce an analog platform that uses light to address transducers and thereby shape ultrasound wavefront.
Cholesterol Shapes How the Brain’s Neurotransmitter Transporter for Serotonin Works
New research shows that membrane cholesterol fine-tunes serotonin, dopamine, and norepinephrine transporters—affecting neurotransmitter recycling, drug responses, and potentially brain disorders.
Lingonverse: Micropropagated Berry Intelligence
Scientists custom-develop new, powerful forms of artificial intelligence (AI) to help farmers and agricultural scientists grow these berries better. Think of it like giving them a super-smart assistant that never gets tired.
Reducing Unreasonable Lab Requests with Demand Management Tools
This quality improvement project was implemented to reduce unnecessary laboratory testing requests with a focus on chromogenic and coagulation tests to improve efficiency and productivity in the hematology department of a hospital in Saudi Arabia.
TCF1 as a Key Regulator of the Hybrid EMT State in Breast Cancer: Balancing Self-Renewal and Differentiation
Triple-negative breast cancer (TNBC) harbor a unique hybrid epithelial/mesenchymal (E/M) subpopulation that conveys stemness and metastasis. Our work unravels a unique role for TCF1/Wnt/ERK/CDK4/6 signaling in driving the hybrid EMT state and its potential for therapeutic intervention in TNBC.
