Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
High-quality alligator gar chromosome-level genome aids in exploring its internal invasion mechanism
Our study generated a high contiguity, completeness, and accuracy genome assembly of alligator gar at the chromosome level using Oxford Nanopore Technology and Hi-C sequencing techniques, deepening our understanding of the genomic basis of its ecology, evolution, and invasiveness.
Spatio-temporal rainfall variability and trends using a Kriging-interpolation and Innovative trend analysis approach: the case of Wolaita zone, south Ethiopia
Understanding climate change and its local impacts has become crucial in addressing global sustainability challenges.
Aging-dependent loss of functional connectivity in a mouse model of Alzheimer’s disease and reversal by mGluR5 modulator
Alzheimer’s disease is challenging to tackle: it can affect the brain years before symptoms like memory loss arise. Yet, this slow progress gives us a long window where early detection could slow or stop its progression. Our study dives into how brain imaging and mouse models can help us get there.
E- Learning experience of the medical profession’s college students during COVID-19 pandemic in Saudi Arabia
This study explored the e-learning experience of the students of the colleges of health sciences with regard to the technical preparedness, academic achievements, e-learning advantages and limitations.
Behind the Paper: How IL-6 shapes the anti-tumor battle and supports TGFβ immune modulatory vaccines in pancreatic cancer
The study highlights that the antitumor efficacy of TGFβ-specific T cells in pancreatic cancer critically depends on IL-6 signaling. IL-6R blockade compromises the immune response by reducing vaccine-induced T-cell infiltration as well as increasing immunosuppressive tumor-associated macrophages.