New preprint suggests the mechanism of cross-kingdom host jumps

"One day, while walking along a park, I was suddenly kicked in the head by an emerging pathogen that fell from an oak tree. Two weeks in a hospital — it was LOX-positive!"
This cannot happen, and it is really just a stretch joke. But it reflects some ideas from my new preprint on BioRxiv.
Indeed, some emerging bacterial pathogens show cross-kingdom properties. It means they can "jump" from one species to another even if they belong to different kingdoms of life. For instance, some plant pathogens can affect immunocompromised people or people with cystic fibrosis.
In the course of our previous research, we have suspected that oxylipin bacterium-host signalling could contribute to plant-human host jumps. In this research, we further elaborate this hypothesis and try to find new bioinformatic evidence for it from network text analysis, phylogenetics, and binding site structure analysis.
Caution: this article is a preprint, and it is not yet peer-reviewed. Please read it carefully. And I will appreciate your comments, criticism, and suggestions (if any).
These findings have been presented at two conferences: FEMS 2022 (Belgrade, Serbia) and ISMB 2022 (Madison, Wisconsin, USA). Please find the video of ISMB 2022 presentation below.
UPD from 11.05.2024: conference presentation details added, preprint version updated, communities updated
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