Unraveling the Sugary Code: N-Glycosylation's Impact on Protein Conformation and its Link to Disease

In the intricate dance of cellular processes, a seemingly modest tweak known as N-glycosylation takes center stage. This post-translational modification endows proteins with a sophisticated sugar code, dictating their conformation, assembly, and, crucially, their roles in various diseases.

Gabriela Chiosis and 2 others

Feb 27, 2024

Behind the Paper

Unveiling the Role of Protein Glycosylation: Insights into Conformational Dynamics and Disease Mechanisms

Glycosylation plays a critical role in controlling normal cell functions as well as disease-related conditions. Understanding how sugar modifications impact proteins, including their conformations and interactions, is crucial for unraveling the causes of diseases and developing targeted treatments.

Gabriela Chiosis and 2 others

Jun 20, 2023

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Giorgio Colombo

Unraveling the Sugary Code: N-Glycosylation's Impact on Protein Conformation and its Link to Disease

Unveiling the Role of Protein Glycosylation: Insights into Conformational Dynamics and Disease Mechanisms

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