Tomás Clive Barker Tejeda

PhD Student, CEMBIO, Universidad CEU San Pablo
  • Spain

About Tomás Clive Barker Tejeda

I am a pre-doctoral researcher and PhD candidate, member of CEMBIO since November 2016. Both my Bachelor’s and Master’s thesis discussed the application of GC-MS in the study of allergic diseases. The former was applied to a clinical study of grass-pollen sublingual allergen-specific immunotherapy (published in Allergy in 2020), while the latter analysed a transgenic mice model of allergic enteritis in collaboration with the Paul Ehrlich Institut in Frankfurt (currently under review). I was awarded the Excellence Scholarship by the UCM to pursue my Master’s Degree.

I am currently investigating a multiplatform study of cow’s milk allergy in young infants, their mothers, and grandmothers, under the supervision of Dr Marina Pérez Gordo and Dr Alma Villaseñor. This has allowed me to present my work at several international congresses (PBA 2017, EAACI 2019, 2020, 2021 and 2023, and Metabolomics 2020, 2021 and 2023). I had the great honour of receiving the Metabolites Best Poster Award for my work in Metabolomics 2020, and the 2023 Metabolomics Society Student Travel Award. In 2022, I was able to spend three months in the Britz-McKibbin lab at McMaster University, Canada, as an international PhD student, applying the innovative multisegment injection (MSI)-CE-MS methodology to my thesis project.

The results from metabolomics, genomics, and the integration of both in the three-generation cohort of our study were published recently in Nature Communications.

I am interested in developing and applying methodologies targeting bile acids and other relevant gut microbiota metabolites, as well as integrating metabolomics with genomics techniques that characterize the gut microbiota (such as 16S rRNA sequencing and shotgun metagenomics). My goal is to paint a fuller picture of microbiota and host interactions and how they relate to health status and disease, especially regarding allergic pathologies.

Intro Content

Nature Communications

Human gut microbiome and fecal metabolome: a detailed description across three generations reveals the uniqueness of infants vs their elders

In this multi-omics study we provide unprecedented insights into the human gut microbiome, revealing significant differences across three generations of the maternal lineage. Our research provides a valuable resource for future studies aiming to improve childhood health outcomes.


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