Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Hyperphosphorylated tau polymerizes into amorphous cytotoxic aggregates
One pathological hallmark of Alzheimer’s disease is the accumulation of neurofibrillary tangles that are primarily consisted of hyperphosphorylated tau. Our results highlighted the impact of hyperphosphorylation on tau leading to the spontaneous formation of amorphous cytotoxic aggregates.
Understanding pathoadaptation of the periodontal microbiome
It is now becoming critical to understand how a synergistic community of virulent bacteria can persist below the gum line, modulate inflammatory responses, and promote gum infections and inflammation, with strong implications in several systemic diseases in adults.
Longitudinal and Latitudinal Split-Gate Field-Effect Transistors for NAND and NOR Logic Circuit Applications
Structural engineering of split-gate FET (SG-FET) is carried out to achieve two different homogeneous MoS2-based switching devices, whose SG gap direction are longitudinal (AND-FET) and latitudinal (OR-FET) to the channel direction.
Twin physically unclonable functions based on aligned carbon nanotube arrays
Aligned carbon nanotube arrays have random characteristics, such as chirality and position, perpendicular to the growth direction and identical characteristics along the growth direction. We proposed and realized twin physically unclonable functions based on CNTs for secure communication.
Synthesis of Aryldifluoromethyl Aryl Ethers via Nickel-Catalyzed Suzuki Cross-Coupling Reactions
An efficient synthesis of aryldifluoromethyl aryl ethers was established via nickel-catalyzed aryloxydifluoromethylation. Using this protocol, difluoromethylated PD-1/PD-L1 immune checkpoint inhibitors were comveniently achieved with enhanced antitumor efficacy over the non-fluoro congeners.
Magnetic aerogel for hazardous dye and toxic metals remediation
A group of academic principle investigator's from multiple countries (Poland, Taiwan and India) were developed an efficient adsorbent of magnetite nanoparticles decorated PVA-modified PEI-h-BNNSs aerogel (adsorbent) for efficiently capturing of heavy metals and organic dyes from an aqueous solution.
