Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
GRAMD1C-mediated cholesterol transport regulates autophagosome biogenesis and mitochondrial bioenergetics
In their study, Ng and coworkers identified the cholesterol transport protein GRAMD1C as a negative regulator of autophagy and mitochondrial bioenergetics and explored its link to Clear Cell Renal Carcinoma (ccRCC).
Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors
Polymersomes are an excellent platform to generate cell-like entities with life-like behaviour. Inspired by the circadian rhythm, we explored feedback-controlled networks between chemically communicating polymersome populations.