Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Biomarkers for ideal protein: rabbit diet metabolomics varying key amino acids
This paper primarily aims to explore ideal protein biomarker signatures through both targeted and untargeted metabolomics analysis in a rabbit model.
Morphology shaped community dynamics in early animal ecosystems
Early animals from the Avalonian Ediacaran look unlike anything alive today. We used community ecology techniques to understand succession processes, tiering, and community composition.
Which algorithm is just right for my data?
Artificial intelligence is impacting research and drug discovery and such techniques have been developed and applied for decades for structure activity analysis. Yet the question of which algorithm to use and how many molecules are needed is still an open one. We found a Goldilocks zone may apply.
Early life cold and heat exposure impacts white matter development in children
Brain scans of more than 2500 preadolescents suggest that early life exposure to heat and cold may have lasting impacts on brain white matter. The study, published in Nature Climate Change, highlights the vulnerability of foetuses and children to extreme temperatures
Targeting fatty acid synthase in preclinical models of triple-negative breast cancer brain metastases synergizes with chemotherapy and impairs invasion
Metastatic triple-negative breast cancer cells need to acquire the ability to produce new fatty acids to more effectively colonize the brain. Our study investigates how this metabolic vulnerability can be targeted to increase efficacy of chemotherapies and impair cancer cell invasion.
