Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Breakthrough in Stereoselective C(sp³)–H Alkylation: Nickel Catalysis Unlocks Efficient Synthesis of Chiral Heterocycles
The Kong group report a Ni-catalyzed enantioselective C(sp³)–H alkylation of saturated heterocycles using olefins, enabling efficient construction of chiral C(sp³)–C(sp³) bonds. Applications include late-stage drug diversification and concise syntheses of bioactive alkaloids.
The jet stream, floods, and droughts in Central Europe: A six-hundred year perspective
New 3-dimensional climate reconstructions allow studying the variability of the Atlantic-European jet stream back to the 15th century. The analysis shows that extreme climate events were related to excursion in the jet.
