Precise recognition of benzonitrile derivatives with supramolecular macrocycle of phosphorylated cavitand by co-crystallization method
While establishing specific lock-and-key recognition for structure-based drug design is typically based on the computational method, co-crystallization could mimic molecular docking. Herein, we report a supramolecular macrocycle that can precisely recognize benzonitrile derivatives.
High-temperature superconductivity with zero resistance and strange-metal behaviour in a nickelate material
Evidence of high-temperature superconductivity under pressure was recently found in a bulk nickelate material, but zero-resistance was not seen. In a new study using a different high pressure technique, zero-resistance is revealed, as well as other clues for understanding the superconductivity.
Carbenoid-involved Reactions Integrated with Scaffold-based Screening Generates a Nav1.7 inhibitor
The synthetic accessible virtual inventory (SAVI) has attracted attention due to its compound synthesis accessibility and structural diversity. The carbenoid-involved reactions (CIR) are suitable for enumerating SAVI.
Recycling of silicon solar panels through a salt-etching approach
We report a simple salt-etching approach to recycle Ag and Si from end-of-life Si solar panels without using toxic mineral acids and generating secondary
pollution.
Behind the paper: Unraveling the molecular mechanism behind COVID-19 pulmonary pathologies associated with ferroptosis
How we found that ferroptosis is a key driver of lung damage in severe COVID-19 patients,
By Baiyu Qiu, Fereshteh Zandkarimi, Anjali Saqi and Brent R. Stockwell
