Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Phosphorus deficiencies invoke optimal allocation of exoenzymes by ectomycorrhizas
Our study emphasizes the key role of symbiotic ectomycorrhizal fungi in phosphorus acquisition. By Dr. Melanie Jones, UBCO and Dr. JM Kranabetter, BC MOF
Straight Swimming to the Intestinal Epithelium
In the gastrointestinal tract, smooth swimming facilitates invasion of intestinal epithelial cells by Salmonella Typhimurium. We found that the master regulator HilD coordinates these processes and that McpC, a chemotaxis protein, promotes straight swimming and optimal invasion.
A Diet-Microbe-Epithelia Metabolic Trilogue in the Stressed Gut
Gut epithelial integrity is dynamically shaped by microbial signals amenable to environmental and psychological modulation. Here we dissect dietary impact on psychological stress-induced gut microbial remodeling and how this is metabolically linked to stem cell proliferation and epithelial renewal.
Discovering a new ACE2 isoform; rallying to understand SARS-CoV-2 infection
COVID-19 forced a suspension to our primary ciliary dyskinesia (PCD) diagnostic service. Re-purposing nasal epithelial cell RNAseq data and bioresource, three University of Southampton groups joined forces and found a new “short” isoform of ACE2, the cell surface receptor for SARS-CoV-2 virus.
Long-read metagenomics using PromethION uncovers oral bacteriophages
integrating both PromethION and HiSeq data of >30 Gb per sample with low human DNA contamination
