Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Global biomarkers of sepsis-causing bacteria investigated through the lens of multi-omic approaches
Bringing together some of Australia’s leading biomedical microbiologists and bioinformaticians to develop a reference bacterial sepsis dataset.
Tsunami-driven, transoceanic spread of microbial pathogens impacting cetacean health and conservation
This post refers to the very interesting, seminal article by Dr James T. Carlton and coworkers, published six years ago and dealing with an unprecedented, tsunami-driven, transoceanic spread of marine organisms following the dramatic 2011 earthquake in Eastern Japan (1).
Partner choice, confounding and trait convergence all contribute to phenotypic partner similarity
People in partnerships are more similar to one another than random pairs. However, it is currently unclear what causes this similarity: mate choice, confounding, indirect assortment? Does similarity change with time? In this work, we use ~52000 couples from the UK Biobank to answer these questions.
1,2,4,5-Tetrazine-tethered probes for fluorogenically imaging superoxide in live cells with ultrahigh specificity
Specific detection of cellular superoxide is challenging. Here, the authors designed 1,2,4,5-tetrazine based fluorogenic probes for specific and sensitive imaging of superoxide, and applied them in high throughput screening of modulators of oxidative stress.
First phase II/III trial to verify the efficacy and safety of trifluridine/tipiracil plus bevacizumab as second-line treatment for patients with metastatic colorectal cancer
Contributors: Yasutoshi Kuboki and Takayuki Yoshino;
Department of Experimental Therapeutics and Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan
