Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Brainstem neuromelanin and iron MRI are novel imaging diagnostic markers for idiopathic and LRRK2 Parkinson’s disease.
Dopaminergic neuronal death in Parkinson’s disease is reflected by the loss of neuromelanin in substantia nigra and locus coeruleus. A novel automatic brainstem atlas of MRI neuromelanin-sensitive and iron images was used to differentiate Leucine-rich repeat kinase 2 gene carriers (LRRK2-PD) and idiopathic Parkinson’s disease.
New bioengineering strategies to improve crop photosynthesis and address global crop growing challenge
A study led by University of Liverpool scientists has revealed a new way of using synthetic biology to improve crop growth, meeting a significant challenge to increase crop productivity in a changing climate with a growing population.
Reversal of the diabetic bone signature with anabolic therapies in mice
Bone anabolic agents restore bone mass, architectural integrity, and resistance to fracture by reversing the diabetic bone signature at the tissue, cell and transcriptome levels.