Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Bioengineering & Biotechnology
Harnessing Type I CRISPR–Cas systems for genome engineering in human cells
Using a FokI fusion design, we show that Type I CRISPR-Cas systems can be expressed, reconstituted, and faithfully trafficked to the nucleus for genome engineering in human cells
Nanoparticle drug delivery targets an intracellular source of pain
With a need to develop new non-opioid analgesics, pH-responsive nanoparticles may offer an alternative strategy for improving analgesic drug efficacy and duration of action.
