Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: General & Internal Medicine
The genetic architecture and biology of youth-onset type 2 diabetes -- the
A model for common disease both satisfying and obvious -- or is it?
SARS-CoV-2 spike protein-ACE2 interaction increases carbohydrate sulfotransferases and reduces N-acetylgalactosamine-4-sulfatase by p38 MAPK
This article describes how increased chondroitin sulfate may contribute to the pathogenesis of Covid-19 due to increased biosynthesis and reduced arylsulfatase B-mediated degradation.
A Detour for Prostate Cancer Cell Survival and Growth
Second generation AR antagonists, abiraterone and enzalutamide, induce aberrant HGF/MET and Wnt pathways leading to increased XPO1 expression and ribosomal biosynthesis in double-null prostate cancer (DNPC). However, treatment with XPO1 and ribosomal inhibitors showed an improved antitumor response.
