Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Microbiology
Reactive Metal Boride Nanoparticles Trap Lipopolysaccharide and Peptidoglycan for Bacteria-Infected Wound Healing
Antibacterial wound healing approaches often target bacteria but overlook the inflammation response caused by products released by dead bacteria. The authors develop MB nanoparticles to prevent both infection and excessive inflammation by trapping the key component of bacteria, LPS/PGN.
Cyclic di-GMP is central to the function of T3SSs
Cyclic di-GMP transduces extracellular stimuli into intracellular responses to modulate important biological processes. Little is known about how extracellular signals modulate c-di-GMP metabolism to control T3SSs. Here is the answer.
Putting the pieces together: Developing a new tool to comprehensively update the Mycobacterium tuberculosis H37Rv reference sequence
H37Rv is the most widely used M. tuberculosis strain, and its genome is the reference sequence for this pathogen. Chitale et al. presents a bioinformatic pipeline for accurate assembly of bacterial genome sequences, and use it to provide important updates to the M. tuberculosis reference genome.
Spread it out: mRNA advantage for antibody coverage against SARS type viruses
To what extent do vaccine and infection determine the antibody responses of an individual in terms of breadth and magnitude to a wide range of SARS-CoV-2 and relevant viruses? Here is your answer.
Do dirty viruses make you sicker?
Recent paper we contributed to looked at the role of defective viral genomes in the disease after influenza virus infection.