Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
The missing intermediate to form ethanol from carbon dioxide
So far ethanol and ethylene have been suggested as twin products during CO2 electroreduction on copper. Here, via in situ surface-enhanced Raman spectroscopy and density functional theory, we report a specific intermediate for ethanol production, proposing an update reaction mechanism.
Photoreactive fragment pharmacophores explore potential binding sites and provide hits for highly challenging drug targets
Photoaffinity-tagged fragments are increasingly used for convenient hit detection and binding site mapping in early drug discovery. We tackled two important challenges by maximizing the pharmacophore diversity of the core fragments, and by enhancing the labelling efficiency of the photoaffinity tag.
Implementation Strategies in Suicide Prevention
Implementation science is a field which studies the factors needed for ensuring an intervention is used and maintained when deployed in the real world. The goal of our review was to understand the current use of implementation strategies for supporting suicide prevention across diverse settings.
