Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Exploring donor difference in neonatal fecal microbiota transplantation
Using a controlled preterm piglet model, we found rectal fecal microbiota transplantation manifested clinically and microbiologically in a donor-dependent manner. Metagenomic analysis revealed strain-level phylogenetic separation of the engrafted lactobacilli strains according to the donors.
light-triggered, large-area, programmable micro-assembly using a photosensitve polymer
A simple wafer-level micro-assembly technique based on light-triggered change in both surface topography and interfacial adhesion of a soft photo-sensitive polymer is developed, which allows the assembly of diverse materials and functional devices, with the printing size up to 4-inch.
Bis-Schiff base linkage makes gold nanoclusters brighter
We develop an efficient strategy to increase the photoluminescence quantum yield of water-soluble gold clusters at the single-cluster level via formation of bis-Schiff base linkages, and its mechanism is deeply investigated.
Nickel-catalyzed asymmetric hydrogenation of oximes
The asymmetric hydrogenation of oximes to chiral hydroxylamines is a long-standing problem due to the labile N-O bond and inert C=N bond. It has now been enabled by a chiral nickel catalyst with excellent results in which the weak interactions between catalyst and substrate play crucial roles.