Go to the profile of Yu Xiao

Yu Xiao (He/Him)

Senior Researcher, Zhongnan Hospital of Wuhan University
  • China

About Yu Xiao

Researcher at Department of Urology and Biobank focussing on Oncology, Cell Biology, Bioinformatics for pre-clinical study.

Intro Content

Behind the Paper

Integrative single cell atlas revealed intratumoral heterogeneity generation from an adaptive epigenetic cell state in human bladder urothelial carcinoma

A subgroup of bladder cancer cells marked by TM4SF1 expression is a key source of tumor diversity (ITH). These cells, which show stem-cell features and foster various cell types within the tumor, are linked to more advanced cancer stages and poorer outcomes.

Popular Content

Cellular & Molecular Immunology
Behind the Paper

Pedigree analysis of a POLD1 germline mutation in urothelial carcinoma shows a close association between different mutation burdens and overall survival

We found a bladder cancer family in which germline mutations of POLD1 and somatic mutations of FGFR3 were prevalent. We studied the changes in the immune microenvironment in patients with this mutation in our cohort and a TCGA cohort and predicted the prognosis of patients with this subtype.
Go to the profile of Yu Xiao +3
Yu Xiao and 3 others
Oct 10, 2024

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