Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Membrane-anchored DNA nanojunctions enable closer APC-T cell contact in elevated T-cell receptor triggering
Yulin Du, Liping Qiu*, and Weihong Tan* et al. from Hunan University develop membrane-anchored geometrically stable DNA nanojunctions to decrease intermembrane spacing at the close contact zone, leading to the exclusion of tyrosine phosphatase CD45 protein and enhancement of T-cell signalling.
The A(H5N1) avian influenza virus and its intriguing trajectories between domestic animals, wildlife and humans
While the SARS-CoV-2 betacoronavirus keeps undergoing mutations, thereby increasing its affinity to target cells and tissues and bypassing antiviral immunity, the highly pathogenic avian influenza (HPAI) virus A(H5N1) has alarmingly emerged, once again, in the global eco-epidemiological scenario.
