Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
FOXQ1 utilizes the KMT2A/MLL complex as a transcriptional co-activator of EMT in breast cancer
Forkhead box Q1 (FOXQ1) recruits the KMT2A/MLL histone methyltransferase to gene regulatory regions by binding to RbBP5. In this study, we uncover the protein interaction mechanism and demonstrate how this transcriptional pathway could be exploited to suppress FOXQ1-mediated EMT and metastasis.
The contribution of turbulence to slow variations in phytoplankton abundance in the world ocean
Why does the amount of phytoplankton in the oceans vary so much from year-to-year? We thought it was because of the pulsation of the oceans due to climate modes. But this was forgetting that the ocean is a turbulent fluid.