Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
A Grand Challenge
Stapled α-helical peptides, can bind to and modulate therapeutic targets that have been historically out of reach with traditional modalities. However, it has been challenging to design stapled peptides that have both good cell permeability and behave well. Our team aimed to address this challenge.
A Retrospective Analysis of Biliary Tract Cancer Patients Presented to the Molecular Tumor Board at the Comprehensive Cancer Center Munich
With the rising importance of precision oncology in biliary tract cancer (BTC), this analysis describes the clinical and molecular characteristics of this patients.
A generative model of memory construction and consolidation
A computational model shows how the hippocampus encodes episodic memories and replays them to train generative neocortical models of the world, so that conceptual and sensory representations of experience can be recombined for imagination and memory.
Getting to 1.5C might need some course adjustments
This blog reports the thinking behind a study undertaken by a team of researchers across Imperial College London and the Met Office Hadley Centre, to look at how climate change mitigation pathways could be adjusted as future information is received, around both climate and technological conditions.
Unveiling the Journey Behind a Breakthrough in Early Detection of Pancreatic Cancer
New paper demonstrates effectiveness of exosome isolation technology in detecting Stage I and II pancreatic ductal adenocarcinoma (PDAC)
How we respond to stressors
Behind the Paper: Risk for diagnosis or treatment of mood or anxiety disorders in adults after SARS-CoV-2 infection, 2020–2022 https://doi.org/10.1038/s41380-024-02414-x