Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Tracking chemical coherence in condensed media
cis-stilbene is a photochemical prototype for cis-trans olefinic photoisomerisation. In our recent work, we show that this process maintains coherence throughout the reaction path, even in liquid-phase. This has interesting implications for the evolutionary favourability of this reaction in biology.
CRISPR Off-Targets: One SNP can make all the difference
In a recent paper, we used ultra-deep sequencing to determine whether CRISPR was introducing or enriching for mutations in cancer genes.
Huntingtin’s new interaction site: a tale of DNAJB1 and HTT’s proline-rich domain
by Sara Maria Ayala Mariscal, Josh Vermaas & Janine Kirstein