Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
The Molecules that were Able to Start Translation
The origin of translation is one of the great mysteries of prebiotic evolution. We present an experimental system that shows how the earliest steps could have occurred.
B Cells: At the intersection of enhanced responses to immunotherapy treatments
B cells have strong clinical significance as drivers of antitumor immunity in triple negative breast cancer. While B cells are known to enhance T cell-mediated tumor killing, we have also uncovered a potential regulatory function, in which they suppress myeloid-derived suppressor cells.
Predicting hospitalization costs via clinical notes
Hospitals only know how much a patient costs once they’ve gone home, making it difficult to plan spending efficiently, but predictive algorithms could help estimate costs early for inpatients.