Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Thyroid hormone receptor β is a newly identified transcription factor to suppress cancer stem cell activity
Cancer stem cells (CSCs) enable adaptive plasticity in tumors that contributes to therapy resistance and poor disease outcomes. Here, we show that thyroid hormone receptor β (TRβ) suppresses CSCs through the transcriptional regulation of CSC-related genes, thereby impeding tumorigenesis.
Behind the Book | The evolution of quantum optics
My new textbook illustrates how quantum optics has come to play an enabling role in many areas of modern science
Cryo-EM Structure of Lipopolysaccharide Transporter LptDE Opens the Door to Antibiotics Design
Bacteria display very different biochemistry from human cells, which can be exploited for designing new antibiotics with less side-effects. Detailed insights into the architecture and function of LptDE transporter complexes has been made possible by new Cryo-EM structures.
