Behind the Paper
The real stories behind the latest research papers, from conception to publication, the highs and the lows
Filtered by: Bioengineering & Biotechnology
Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock
A new vaccine technology combining capture of bacterial pathogens with effective immune-reprogramming biomaterials could overcome common limitations in infection medicine.
An in situ activity assay for lysyl oxidases
Current methods for detecting activity of lysyl oxidases lack specificity and do not provide information on how much activity is occurring in situ. Hydrazide reagents can be used to measure their in situ activity levels in a practicable, sensitive, and specific manner.
Error tolerant barcodes for single-cell sequencing
Synthesising oligonucleotides using blocks of nucleotides to overcome sequencing errors in error prone single-cell RNA-sequencing.
Environmental dimensions of the protein corona
Our understanding of how biomolecules redirect the fate and impact of nanomaterials in the environment is rapidly advancing. We present the emerging work, along with our perspective on next steps in eco-corona studies.
Synthetic biology: Bottom-up meets top-down
We used proton gradients from top-down engineered light-harvesting E. coli to actuate DNA origami nanostructures. The DNA origami, in turn, controls the deformation of bottom-up assembled synthetic cells.